PDF Electrophysiological Foundations of Cardiac Arrhythmias A Bridge Between Basic Mechanisms and Clinical Electrophysiology

Read Electrophysiological Foundations of Cardiac Arrhythmias A Bridge Between Basic Mechanisms and Clinical Electrophysiology

Read Electrophysiological Foundations of Cardiac Arrhythmias A Bridge Between Basic Mechanisms and Clinical Electrophysiology

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This book teaches the fundamental concepts of cardiac electrophysiology with an emphasis on the relationship of basic mechanisms to clinical arrhythmias. Understanding this relationship and the underlying mechanisms of arrhythmogenesis will be valuable to medical students in general and physicians entering the fields of cardiology and clinical electrophysiology, as well as those scientists and clinicians already working in this field. The foundations of electrophysiology are explained in a way that will enable the student/reader to go on to more advanced texts such as Josephson s Clinical Cardiac Electrophysiology by Mark E. Josephson (Wolters Kluwer), who is one of the authors of this book. It is not a complete review of basic cellular electrophysiology and only focuses on aspects that are relevant to the arrhythmogenic mechanisms. Similarly, it is not a complete compendium on electrophysiology of clinical arrhythmias. Only selected arrhythmias are described that best illustrate the translation of the basic electrophysiological mechanism to the clinic. The book is divided into three parts that cover the major mechanisms of arrhythmogenesis: Part I Automaticity, Part II Afterdepolarizations and Triggered Activity, and Part III Abnormal Impulse Conduction and Reentry. Each part starts with a chapter that describes the basic science principles related to that particular mechanism. Topics include: impulse initiation and rate control, membrane currents, conduction, and the effects of programmed electrical stimulation and pharmacologic agents. Subsequent chapters in each part are organized around examples of clinical arrhythmias and then focus on the relevant EP mechanisms and the characteristic responses to interventions. The characteristics of the three different mechanisms are compared and contrasted throughout the text. Each example works through these three key questions: 1. What are the ECG characteristics of the arrhythmia 2. What is the underlying electrophysiological mechanism 3. What are the characteristic properties of the arrhythmia that point to its mechanism Throughout the book, the aspects of basic EP mechanisms and examples from EP studies and pharmacologic interventions are paired with clinical examples. The end result is enhanced understanding of how EP mechanisms and testing relate to arrhythmogenesis in a way that can be applied broadly to a variety of situations in a clinical setting. This definitive book also includes: More than 300 figures, including ECGs and original diagrams that illustrate essential electrophysiology concepts. Case studies of clinical arrhythmias with explanations of how ECG characteristics and the responses to electrical stimulation denote arrhythmogenic mechanisms. Electrophysiological Foundations of Cardiac Arrhythmias by Wit, Josephson, and Wellens is a long overdue text bridging basic science and clinical medicine, thus providing basic scientists, clinical investigators and practicing physicians, unique insights into the mechanisms underlying cardiac arrhythmias. The complex mechanisms responsible for the development of clinical arrhythmias are discussed in detail, but with clarity and appreciation of continuing gaps in our knowledge. -Charles Antzelevitch, PhD, FACC, FAHA, FHRS; Lankenau Institute for Medical Research; Philadelphia, Pennsylvania The Effect of Spironolactone on Morbidity and Mortality in Original Article The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure Bertram Pitt MD Faiez Zannad MD Willem J Academic Careers - Case Western Reserve University Academic Careers Salary offers are extended by Human Resources and will depend on available funding candidates' relevant experience and education internal equity META-INF/MANIFESTMFname/audet/samuel/shorttyping META-INF/MANIFESTMFname/audet/samuel/shorttyping/ShortDictManager$BufferedStreamclassname/audet/samuel/shorttyping/ShortDictManagerclassname/audet/samuel Effect of Carvedilol on Survival in Severe Chronic Heart Original Article Effect of Carvedilol on Survival in Severe Chronic Heart Failure Milton Packer MD Andrew JS Coats MD Michael B Fowler MD Hugo A MED-ED Program List MedEdSeminarsnet Complete Program List All programs below are available to bring to your hospital Icons to the left of the Program title indicate if the program is available live Web of Science Help This list shows the abbreviations used for journal titles as cited works Copy the abbreviated (boldface) title from this list and paste it in the Cited
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